Biomarker Targeted Assay

Thermo Scientific* helps you speed the development of biomarker targeted assays, a critical bottleneck in biomarker research and in the advancement of personalized medicine.

Our integrated, end-to-end liquid chromatography-mass spectrometry (LC-MS) workflows, applications and standard operating procedures make it remarkably easy to develop and optimize high-throughput, quantitative, multiplexed targeted biomarker assays.

• Applications

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High-resolution Full-scan Quantification

High-resolution full-scan quantification is a new, high throughput approach for the quantitative analysis of intact protein and peptides.

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Targeted Selected Reaction Monitoring (SRM)

Thermo Scientific* selected reaction monitoring (SRM) workflows speed the development of biomarker targeted assays for validation and verification of putative biomarkers.

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Protein Characterization

Thermo Scientific* workflows offer a new, high-throughput approach for the characterization of proteins and their variants.

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Our product portfolio includes a full range of sample preparation, instrumentation and software products that work together to provide robust, time-saving workflows for the development of biomarker targeted assays.

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HPLC Columns [2.4um and Smaller]HPLC Columns [2.4um and Smaller]
HPLC columns in particle size 2.4um and smaller.

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Nucleic Acid Purification SystemsNucleic Acid Purification Systems
Nucleic acid purification systems and accessories to process samples from virtually any source with guaranteed sample integrity.

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LC/MS On-Line Sample Prep and Multiplexing SystemsLC/MS On-Line Sample Prep and Multiplexing Systems
The innovative technologies integral to these systems combine the power of automated online sample preparation with Thermo Scientific TurboFlow technology and unique multiplexing capabilities to increase the efficiency of your mass spectrometry workflow.

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Orbitrap LC/MSOrbitrap LC/MS
Orbitrap* LC/MS technology is the recognized standard for accurate mass and high-resolution measurement.

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Magnetic Affinity Separation ParticlesMagnetic Affinity Separation Particles
Paramagnetic particles and activated affinity purification beads for benchtop immunoprecipitation procedures and automated protein separation workflows based on antibody, streptavidin, GST and titanium dioxide ligands.

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Proteases and Protein-Cleaving ReagentsProteases and Protein-Cleaving Reagents
Purified and agarose-immobilized proteases for enzymatic proteolysis (cleavage or digestion) of proteins to facilitate amino acid sequencing, peptide analysis and polypeptide structural characterization.

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MS AccessoriesMS Accessories
A comprehensive range of mass spectrometry accessories to optimize system performance in a variety of applications.

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Spin Columns and Gravity-flow ColumnsSpin Columns and Gravity-flow Columns
Different sizes and types of empty purification columns and filter spin columns for packing desalting resins, agarose beads or other affinity supports to use in microcentrifuge or gravity-flow chromatography procedures.

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MS SoftwareMS Software
Application-specific software for large and small molecule analyses, designed to take users from sample to answer as quickly as possible.

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Standard SystemsStandard Systems
Thermo Scientific Dionex UltiMate 3000 Standard LC systems provide the right solution for demanding microbore, analytical, and semipreparative LC applications. Analytical systems are UHPLC compatible with pressures up to 62 MPa (9000 psi).

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