Targeted Selected Reaction Monitoring (SRM)
Thermo Scientific* selected reaction monitoring (SRM) workflows speed the development of biomarker targeted assays for validation and verification of putative biomarkers.
Our discovery-driven liquid chromatography-multistage mass spectrometry (LC)-MS/MS selected reaction monitoring (SRM) workflow mines data from biomarker discovery experiments and then uses this data to construct targeted biomarker assays that can be applied to clinical research studies. It is now remarkably easy to develop and optimize high-throughput, quantitative, multiplexed targeted biomarker assays.
Combine powerful Thermo Scientific Pinpoint software with the unique analytical power of the Thermo Scientific TSQ family of triple quadrupole mass spectrometers to verify large lists of putative biomarkers more efficiently and rapidly than ever before. Our liquid chromatography (LC), ultra high-pressure liquid chromatography (UHPLC), nano-LC, and automated sampling solutions, along with our broad choice of quality HPLC columns, provide a robust modular system with the performance your laboratory demands. Complementary sample preparation technologies such as Thermo Scientific Pierce enrichment kits help you verify and quantify proteins from complex biological samples. To complete your workflow, we offer, high-quality standards, 96 wellplates, spin columns, buffers, centrifuges, 1D gels and mass spectrometric immunoassay (MSIA) tips.
