Thermo Scientific Orbitrap Mass Spectrometers - Innovation Applied!

High sensitivity quantitation is a demanding science! High resolution, accurate mass (HR/AM) quantitation with a Thermo Scientific* Q Exactive* LC/MS can help. The ultra-high resolution and mass accuracy delivered by Thermo Scientific Orbitrap* technology resolves signal from interferences in complex matrices and lowers the limit of detection. With easy assay set up and data processing workflows, Q Exactive combines high-sensitivity quantitation capacity with HR/AM capability that triples cannot provide.

 It's time to think again. Get the facts to learn more about Orbitrap technology,
its accessibility and affordability!

Scientific Resources and Posters

• Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics Peterson et al. Mol Cell Proteomics 2012 11: 1475-1488.  
  (Q Exactive, Proteomics)
• 1000 Proteins Per Hour [pph] – Maximizing Protein ID From Complex Mixtures (PDF, 521 KB) 
  (Orbitrap Velos Pro MS; Proteomics)
• A Quadrupole-Orbitrap Hybrid Mass Spectrometer Offers Highest Benchtop Performance for In-Depth Analysis of Complex Proteomes (PDF, 2.53 MB) 
  (AN552; Thermo Scientific* Q Exactive* LC-MS/MS; Proteomics)
• HR/AM Targeted Peptide Quantitation on a Q Exactive MS: A Unique Combination of High Selectivity, Sensitivity and Throughput (PDF, 497 KB) 
  (AN554; Q Exactive LC-MS/MS; Proteomics)
• Quantifying Peptides in Complex Mixtures with High Sensitivity and Precision Using a Targeted Approach with a Hybrid Linear Ion Trap-Orbitrap Mass Spectrometer (PDF, 1.24 MB) 
  (AN557; Orbitrap Elite MS; tides in Complex
  Mixtures Proteomics)
• User Poster: Accurate Neutral Loss-assisted Shotgun Lipidomics (ANLA-SL) for Ultra High-throughput Analysis of Cellular Lipidomes (PDF, 2.33 KB) 
  (Q Exactive LC-MS/MS; Lipidomics)
• Poster: Breaking the 2000-Protein Barrier in a Standard LC Run Using a New Orbitrap Benchtop Instrument (PDF, 1.6 MB) 
  (Q Exactive LC-MS/MS; Proteomics)
• Relative Quantitation of TMT — Labeled Proteomes - Focus on Sensitivity and Precision (PDF, 1.4 MB) 
  (AN566; Orbitrap Elite, LTQ Orbitrap Velos, Isobaric tagging, Quantitative precision, Quantitative accuracy)
• Poster: Multiplexing SIMs on Novel Orbitrap MS w/Quadrupole Mass Filter to Increase Sensitivity for Peptide Quan (PDF, 329 KB) 
  (ASMS 2011)
• Poster: Increased Analytical Performance on a Hybrid Linear Ion Trap-FTMS Mass Spectrometer with a High-Field Orbitrap (PDF, 329 KB)
  (ASMS 2011)

Scientific Resources and Posters

• Robust Ultra High Sensitivity Quantitative Analysis using Low Flow LC/MS/MS and Reduced Phospholipid Matrix Effects. Myth or Reality? (PDF, 118 KB)
• Simultaneous, Fast Analysis of Melamine and Analogues in Pharmaceutical Components Using Q Exactive - Benchtop Orbitrap LC-MS/MS (PDF, 144 KB)
• Utilizing a Non-Targeted HR/AM-MS Method to Accelerate Quantitative Throughput for In-Vitro Metabolic Profiling (PDF, 273 KB)
• Label-Free High Throughput Compound Library Screening Using Multiplexed LC/MS (PDF, 181 KB)
• Utilization of High Resolution LC-MS for Screening and Quantitative Analysis of Pesticides in Food Matrix using a Q Exactive Bench Top Orbitrap Platform (PDF, 795 KB)
• ASMS 2012: HR/AM Targeted Peptide Quantification on Q Exactive: A Unique Combination of High Selectivity, High Sensitivity and High Throughput (PDF, 303 KB)