A unique solution for difficult separations in both reversed phase and normal phase HPLC and LC/MS applications.

Porous graphitic carbon (PGC, Hypercarb) has unique properties as a stationary phase in high performance liquid chromatography (HPLC). Its chemical surface properties distinguish it from more conventional LC packings such as bonded-silica gels and polymers. PGC behaves as a strongly retentive alkyl-bonded silica gel for non-polar analytes, however its retention and selectivity behavior towards polar and structurally related compounds is very different from conventional C18 columns.

Hypercarb Columns offer:

• Exceptional retention of very polar analytes
• Separation for structurally related substances
• pH stablility from 0 to 14, and are not affected by aggressive mobile phases
• The ideal solution for high temperature applications

Physical Properties of PGC

Available Literature

For access to the following literature please register now!

Applications Notebook, Issue 1

• Online interactive version
• iPad optimized version
• PDF (3.67MB)

Method Development Guide for Hypercarb Columns

• PDF (1.31MB)

Learn More

• Ordering Information
• 2010/2011 Thermo Scientific Chromatography Catalog

Thermo Scientific Hypercarb Columns

• Hypercarb Columns (3 μm)
• Hypercarb Columns (5 μm)
• Hypercarb Columns (7 μm)
• Hypercarb KAPPA Capillary Columns
• Hypercarb Nanobore Columns
• Hypercarb Preparative Columns (5 μm) 
• Hypercarb Preparative Columns (7 μm)
• Hypercarb High Temperature Columns (3 μm)
• Hypercarb High Temperature Columns (5 μm)
• Hypercarb Drop-in Guard Cartridges 
• Hypercarb DASH™-HTS HPLC Columns