Protein Denaturants and Chaotropes
Chaotropic and denaturing chemical agents, including urea and guanidine hydrochloride, to disrupt water interactions and promote hydrophobic protein and peptide solubilization, elution, refolding and structural analysis.
Our collection of protein-grade denaturing reagents.
Crosslinking and Protein Modification Methods »
Protein Electrophoresis »
Thermo Scientific* Pierce 8M Guanidine-HCl Solution is an accurately formulated, ready-to-use solution of guanidine hydrochloride, that can be easily diluted and pH-adjusted to any concentration below 8M.
Thermo Scientific* Pierce Guanidine-HCl is pure, crystalline guanidine hydrochloride, a denaturant with many protein research applications.
Thermo Scientific* Pierce Urea is pure, crystalline urea, a protein denaturant with low UV-absorptivity.