Metabolic Labeling Reagents for Proteins

Bioorthogonal azide-modified amino acids, sugars and other compounds for metabolic incorporation into proteins and macromolecules to enable labeling and chemoselective conjugate with alkyne or phosphine reagents via Staudinger ligation chemistry.

Never satisfied with the status quo, we continue to develop products to make use of new technologies for powerful new methods of analysis. Our growing line of Staudinger ligation reagents are a perfect example of this innovation.

Learn more:
Azide-Phosphine (Staudinger Ligation) Reagent Guide »
In Vivo Metabolic Labeling and Ligation »
Staudinger Ligation (Azide-Phosphine) Reaction Chemistry »

DyLight* Fluor Phosphine Reagents

Thermo Scientific* DyLight Fluor Phosphine Reagents are phosphine-activated fluorescent dyes for specific labeling and detection of azide-tagged molecules, which enables use of fluorescence imaging in metabolic labeling strategies.

Pierce* Azido-Sugars

Thermo Scientific* Pierce Azido-Sugars (GlcNAz, GalNAz and ManNAz) are azide-labeled sugars that provide a highly specific approach for studying glycoproteins through in vivo metabolic labeling and chemoselective ligation.

Pierce* Biotin-PEG3-Phosphine

Thermo Scientific* Pierce Biotin-PEG3-Phosphine is a biotinylation reagent for labeling azide-containing molecules, which enables biotin-based detection and affinity purification of molecules via Staudinger ligation strategies.

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