Pegylation Reagents

Activated linear and branched derivatives of polyethylene glycol (PEG) for pegylation and PEG-modification of peptides and proteins via primary amines and sulfhydryl groups to increase solubility, prolong stability and reduce immunogenicity.

Our selection of premium, high-quality, defined-length PEG compounds for peptide and protein modification.

Learn more:
PEG (Polyethylene Glycol) Reagent Product Guide »
Crosslinkers at a Glance »
Crosslinker Selection Guide »
Crosslinking and Protein Modification Methods »

Pierce* Carboxy-PEG-Amine Compounds

Thermo Scientific* Pierce CA(PEG)n Compounds are pegylated amino acids of the form carboxy-PEG-amine, where n equals 4 to 24 polyethylene glycol units, and are useful for a variety of surface- and molecule-pegylation applications.

Pierce* Carboxy-PEG-Lipoamide Compounds

Thermo Scientific* Pierce CL(PEG)12, or carboxy-PEG12-lipoamide, is a carboxyl- and bidentate thiol-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify quantum dots, and silver or gold surfaces a

Pierce* Carboxy-PEG-Thiol Compounds

Thermo Scientific* Pierce CT(PEG)12, or carboxy-PEG12-thiol, is a carboxyl- and sulfhydryl-terminated compound that contains a 12-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magne

Pierce* Methyl-PEG-Amine Compounds

Thermo Scientific* Pierce MA(PEG)n Compounds are methyl- and amine-terminated polyethylene glycol reagents, where n equals 4 to 24 PEG units, that are useful for a variety of surface-modification and molecule-pegylation applications.

Pierce* Methyl-PEG-Lipoamide Compounds

Thermo Scientific Pierce ML(PEG)4, or methyl-PEG4-lipoamide, is a methyl- and bidentate thiol-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify quantum dots, silver and gold surfaces and magnetic partic

Pierce* Methyl-PEG-Maleimide Branched Reagents

Thermo Scientific* Pierce TMM(PEG)12 is a three-branched, polyethylene glycol compound (3 times 12 PEG units) activated with a maleimide group for covalent pegylation of sulfhydryls on proteins (e.g., cysteines) or assay surfaces.

Pierce* Methyl-PEG-Maleimide Reagents

Thermo Scientific* Pierce MM(PEG)12 is a methyl-terminated, polyethylene glycol compound (3 times 12 PEG units) activated with a maleimide group for covalent pegylation of sulfhydryls on proteins (e.g., cysteines) or assay surfaces.

Pierce* Methyl-PEG-NHS-Ester Branched Reagents

Thermo Scientific* Pierce TMS(PEG)12 is a three-branched, polyethylene glycol compound (3 times 12 PEG units) activated as an NHS ester for covalent pegylation of primary amines (e.g., lysines) on proteins or assay surfaces.

Pierce* Methyl-PEG-NHS-Ester Reagents

Thermo Scientific* Pierce MS(PEG)n reagents are methyl-terminated, polyethylene glycol compounds (n equals 4 to 24 PEG units) activated as NHS esters for covalent pegylation of primary amines on proteins (e.g., lysines) or assay surfaces.

Pierce* Methyl-PEG-Thiol Compounds

Thermo Scientific* Pierce MT(PEG)4, or methyl-PEG4-thiol, is a methyl- and sulfhydryl-terminated compound that contains a 4-unit polyethylene glycol (PEG) spacer and is used to modify surfaces such as quantum dots, monolayers and magnetic pa

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