Nucleic Acid Synthesis and Labeling
High-quality oligonucleotide synthesis and labeling reagents, with expertise in protection chemistries, manufacturing scale up and innovative purification strategies. Our phosphoramidites, labeled amidites and specialized nucleoside compounds are used in many cutting edge nucleic acid diagnostic kits, therapeutics and research products.
Process development, optimization and in-house technical expertise enables us to customize processes from gram to ton quantities for customers in research, molecular diagnostics and therapeutics.
Amidites for Amino- and Phosphoro-modifications
Thermo Scientific* Modifying Phosphoramidites are for the addition of a primary amine to the 5' position of an oligonucleotide or to incorporate an amine within the sequence and Phosphorylating Phosphoramidites are used for addition of
Amidites for DNA Synthesis
Thermo Scientific* Standard DNA Phosphoramidites utilize standard base protection that ensures quality and reliability for oligonucleotide synthesis.
Amidites for DNA synthesis – TheraPure*
Thermo Scientific* TheraPure DNA Phosphoramidites are ideal for the most demanding applications of synthetic DNA oligonucleotides due to controlled levels of critical reactive impurities, controlled water content, and ultra high purity.
Amidites for Fast Deprotection Conditions
Thermo Scientific* Fast Deprotect Phosphoramidites are ideal in applications requiring mild deprotection in order to preserve the integrity of oligonucleotides containing sensitive dyes, labels, or other modifications.
Amidites for fluorescent labeling - DyLight* Phosphoramidites
Thermo Scientific* DyLight Fluorescent Labeled Phosphoramidites feature absorption and emission spectra suitable for a broad range of applications and can be used in research applications without the constraints of licensing and royalty fees
Amidites for RNA and 2'-Modifications
Thermo Scientific* Standard RNA Phosphoramidites ensure quality and reliability for RNA oligonucleotide synthesis.
Amidites for RNA and 2'-Modifications – TheraPure*
Thermo Scientific* TheraPure RNA Phosphoramidites are ideal for challenging RNA syntheses due to controlled levels of critical reactive impurities and limited water content.
Amidites with Nucleoside Modifications
Thermo Scientific* Modified Nucleoside Phosphoramidites are used in specialty applications requiring high quality and performance.
Anchored Oligo dT
Thermo Scientific* Anchored Oligo dT is ideal for synthesizing long cDNAs from mRNAs carrying poly-A tails.
DyLight* NHS Esters
Thermo Scientific* DyLight NHS Esters require no licensing for research applications and are suitable for use in multiplex PCR assays.
