Antibody Fragmentation Kits
Optimized reagents and kits based on immobilized papain, pepsin and ficin proteases to selectively cleave IgG and IgM immunoglobulin molecules into Fab, Fab', F(ab')2 and Fc antibody fragments for use in immunodetection and immunoassay procedures.
We've taken the guesswork out of Fab and F(ab)2 preparation. Our kits use well characterized antibody cleaving techniques but extend the efficiency and recovery that is possible through a variety of exclusive innovations.
Antibody Production and Purification »
Antibody Fragmentation »
Thermo Scientific* Pierce F(ab')2 Preparation Kits use immobilized pepsin protease to selectively digest whole human and other IgG antibodies to make F(ab')2 fragments that retain antigen binding activity.
Thermo Scientific* Pierce Fab Preparation Kits use immobilized papain protease to digest human or mouse IgG antibodies to make separate Fab and Fc fragments and subsequently to purify the Fab using Protein A agarose.
Thermo Scientific* Pierce Mouse IgG1 Fab and F(ab')2 Preparation Kits use immobilized ficin protease to efficiently digest mouse IgG1 into Fab or F(ab')2 fragments, depending on the c