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ThermoScientific
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Custom Phosphoramidites

Thermo Scientific* Milwaukee custom phosphoramidites are available in multiple protection chemistries, synthesis scales, purification strategies, and QC methods.
We can respond to new and evolving chemistries and offer superior development and manufacturing services that meet your needs every step of the way, from concept to product. Development teams consist of R&D scientists, experienced synthetic chemists and bioprocessing engineers, dedicated account representatives to facilitate customer communication, QC and product finishing to ensure successful scale-up and consistent product quality, as well as rigorous project management from start to finish. We are experienced in new product development, process improvement projects and final kit assembly, with clients that include distinguished companies serving the molecular diagnostic, therapeutics, and basic research markets. We recognize that specifications can evolve over the life of a product. An ISO9001 registered quality system allows for flexibility to respond to your changing requirements while maintaining all product and process documentation. Changes are carefully reviewed and implemented through a formal change control process.
 
 
 
 
 
Thermo Fisher Scientific (Milwaukee) is the leading expert in the manufacture of phosphoramidites, producing phosphoramidites that are used in many cutting edge nucleic acid-based diagnostic kits, therapeutics, and enabling research products.

Specialties include:

  • Modifications of the 2' position including O-methyl, TBDMSi and fluoro
  • Modifications of the 5' position with acid labile, base labile, or photolabile groups
  • Base modifications including halogenations, alkylations, and others
Product Finishing and Testing Services

Thermo Fisher Scientific offers a full range of processing, dispensing, packaging and labeling services. These include:

  • Formulation capabilities from milliliters to thousands of liters
  • Lyophilization and drying
  • Automated fill and transfer systems
  • Packaging options (including light- and moisture-sensitive)
  • Label formatting and bar-coding
  • Component testing including NMR, mass spectrometry, and enzymatic assays

In combination with the custom packaging and labeling services, the Product Finishing group offers “full-service” kit assembly. Materials manufactured here can be combined with your novel reagents or configured in a unique kit utilizing your custom packaging materials, labels and literature, or these materials can be provided for you.

There are no specifications.

 
 
 
 
 
 
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