Dharmacon* miRIDIAN* microRNA Reagents

miRIDIAN microRNA Mimics

• Synthetic miRNA mimics designed to enter miRNA pathway and act as mature miRNA species
• Supplement native miRNA activity to further decrease steady-state protein levels and study gain-of-function effects

miRIDIAN microRNA Inhibitors

• Synthetic miRNA inhibitors designed to specifically target and irreversibly bind endogenous miRNAs
• Suppress native miRNA activity to increase protein levels and study loss-of-function effects
• Novel, proprietary design confers greater potency and longevity of inhibition

miRIDIAN microRNA Mimic and Inhibitor Positive and Negative Controls

• Mimic and Hairpin Inhibitor Positive Controls to evaluate function and determine optimal assay conditions
• Non-targeting Mimic and Hairpin Inhibitor Negative Controls to distinguish between specific and background effects
• Dye-labeled Transfection Controls to optimize delivery conditions for Mimic and Hairpin Inhibitor experiments

miRIDIAN microRNA Mimic and Inhibitor Libraries

• Collections designed for every human, mouse, and rat miRNA in the current Sanger miRBase Registry
• For phenotypic screening and identification of miRNAs within specific cellular pathways or processes
• Now updated to Sanger miRBase Sequence Database version 13.0