14.3.3 pan Ab-4, Mouse Monoclonal Antibody

14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein.

Host Species: Mouse

Clone: CG15

Isotype: IgG1/k

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: 14.3.3g recombinant human protein

Molecular Weight: 26-33kDa

Positive Control: HeLa cells

Cellular Localization: Cytoplasmic

Pan Ab-4 recognizes β, g, σ and z isoforms of 14.3.3.

Storage Conditions: 4°C, Do Not Freeze

Recommended for:

• Western Blotting
• Immunoprecipitation (Denatured verified)

USA: RUO; Int'l: RUO

References:
1. Laronga C, Yang HY, Neal C, Lee MH. J Biol. Chem 2000.

2. Baldin V. (2000) Prog cell cycle res. 4: 49-60

3. Skoulakis EM, Davis RL. (1998) Mol Neurobiol 3: 269-284.

4. Roberts MR. (2000) Curr Opin Plant Biol 5: 400-405.