14.3.3 proteins are a family of small, widely expressed, highly conserved cytosolic proteins. 14.3.3 proteins bind to and influence the activities of a diverse group of molecules involved in signal transduction, cell cycle regulation and apoptosis, including Raf, PKC, Bad, Cbl, and c-Bcr. Interactions between 14.3.3 and target proteins are strongly influenced by the phosphorylation state of 14.3.3 and the target protein.
Species Reactivity: Human. Others not tested.
Epitope: Not determined
Immunogen: 14.3.3g recombinant human protein
Molecular Weight: 26-33kDa
Positive Control: HeLa cells
Cellular Localization: Cytoplasmic
Pan Ab-4 recognizes β, g, σ and z isoforms of 14.3.3.
Storage Conditions: 4°C, Do Not Freeze
- Western Blotting
- Immunoprecipitation (Denatured verified)
USA: RUO; Int'l: RUO