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ThermoScientific
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Kinetica

Thermo Scientific* Kinetica is a pharmacokinetic, pharmacodynamic, and noncompartmental data analysis application that includes a library of prebuilt, ready-to-use PK, TK, and PK/PD models.
For scientists involved in pharmacokinetic studies who wish to rapidly turn around high-quality analyses and reports, Kinetica is a high-throughput, template-driven pharmacokinetic data analysis application that allows rapid analysis and reporting of data. Kinetica has a unique template format that users can reuse and share. From non-compartmental through to population pharmacokinetic-pharmacodynamic analyses, Kinetica facilitates data analysis and reporting in a flexible environment. Kinetica offers fast high-throughput data analysis for clinical, preclinical, discovery, drug metabolism and drug delivery settings. Kinetica improves the data analysis experience while reducing the need for multiple software packages and associated training.
 
 
 
 
Part Number Description   Quantity
INF-24000 Kinetica
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Unique non-compartmental assistant technology and different standard and advanced PK, PD and PK-PD models. Import data or create datasets, select and tailor computational methodologies, view data with dynamic graphical tools, view individual and study results, export result through the seamless interface to other software.

Non-compartmental Analysis (NCA)

  • Allows rapid view of the analysis via a graphical point-and-click interface
  • Recognizes flagged data for below limit of quantification, outlier, error and missing to allow user to specify the handling of flagged data during the analysis without sacrificing the data themselves

Unit Management

  • Specifies the output pharmacokinetic parameter units as well as input time and concentration units from an extensive list of measurement units
  • Versatile unit conversions are built into the tool for molar conversion

Data Exchange and Storage

  • Simple single file storage
  • Import assistant provides an import of rows and column based data from Microsoft* Excel, ASCII files and direct ODBC-compliant data sources
  • Support for direct Oracle* database import from the Watson bioanalytical LIMS system
  • Predefined table structures for reports
  • Table structure templates include preclinical, clinical, toxicokinetic, sparse study designs

Kinetica for Population PK/PD Analysis

  • Population analysis module
  • Multi-dimensional search option
  • External and internal validation of the population model

Data Analysis

  • Sixty different validated templates, including non-compartmental, PK, PD and PK-PD fitting for standard compartmental and population analyses, absorption, convolution, deconvolution, renal, protein binding, enzyme kinetics, transdermal, in vivo and in vitro correlation, and in vitro dissolution
  • Subset of Microsoft Visual Basic Applications to build custom workflow, analysis settings, data import, data handling and reporting
  • Visual model designer to create multiple compartment models

Testing Agent

  • Performs complete comparison of the calculations of Kinetica
  • Involves testing the features of the software

 
 
 
 
 
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