Process Monitoring and Indust...Process Monitoring and Industrial Instruments ›  Material Characterization and...Material Characterization and Testing ›  Twin Screw Extruders for Phar...Twin Screw Extruders for Pharma Applications › Pharma 16 HME Hot Melt Extruder
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ThermoScientific
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Pharma 16 HME Hot Melt Extruder

The Thermo Scientific* Pharma 16 HME hot melt twin-screw extruder is ideal for small-scale continuous processing in research, development or production in the pharmaceutical industry.
Small-scale melt extrusion allows rapid process development with minimal use of expensive ingredients for defining critical process parameters: It reduces cleanroom space requirements, allows for consistent, controllable processing, and is suitable for PAT. It also minimizes scale-up risk and lowers product changeover time.
 
 
 
 
Part Number Description   Quantity
554-2145 Barrel Length 25:1 L/D; Max Screw Speed 500rpm
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554-2155 Barrel Length 25:1 L/D; Max Screw Speed 1000rpm
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554-2165 Barrel Length 40:1 L/D; Max Screw Speed 500rpm
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554-2174 Barrel Length 40:1 L/D; Max Screw Speed 1000rpm
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Please Note: Availability may vary by country.  
 
 

  • Small footprint
  • Continuous operation
  • High free volume
  • Small process inventory
  • Segmented screws and barrel
  • Removable screws and liners

Environmental Note: Small-scale continuous processing has lower utilities use than traditional batch processes. A small footprint reduces cleanroom volumes and lower ingredient consumption reduces handling and operator exposure.

Self-contained units can be operated with recirculating chillers for reduced water consumption.


Compatible with: We offer a full range of GMP standard ancillaries which are matched to the extruder performance, and can be integrated into the extruder control system. These include, volumetric or gravimetric dosing feeders, air cooled conveyors for product cooling, strand and face-cut pelletisers to make pellets, or chill roll/flaker units for rapid product cooling and flaking.

Recommended for: Materials

  • Medical polymers
  • Drug delivery systems
  • Soft gels

Applications

  • Melt granulation
  • Biomedical compounds
  • Water sensitive products
  • Medical adhesives

 
 
 
 
 
 
 
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