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Eight-Stage Non-Viable Andersen Cascade Impactor

First in its class, the Thermo Scientific* Andersen Series of Non-Viable Cascade Impactors is the original design cited as the world's reference for aerosol particle sizing. The impactors are uniquely defined as a primary standard classification device thanks to performance verification through well established fundamental physical principles.
The Thermo Scientific* Andersen Eight Stage Non-Viable Cascade Impactor is a multi-stage, multi-orifice sampler used in environmental working areas to measure the size distribution and mass concentration levels of solid particulates and liquid aerosols. It is cited within the U.S. Pharmacopeia Chapter 601 as the primary standard characterizing device for aerosols within metered-dose and dry-powder inhalers.
 
 
 
 
Part Number Description   Quantity
20-830 No pump/motor assembly
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20-821 12VDC pump/motor; High capacity preseparator
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20-831 No pump/motor assembly; High capacity preseparator
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20-801 115V pump/motor; High capacity preseparator
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20-800 115V pump/motor
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20-810 230V pump/motor
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20-820 12VDC pump/motor
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Please Note: Availability may vary by country. Show All
 
The combination of a constant flow rate and successively smaller diameter orifices increase the velocity of sample air as it cascades through the sampler, resulting in the impaction of progressively smaller particles in the succeeding stages. Operating at 28.3 liters per minute (LPM) the particle fraction ranges from 0.4 to > 10.0 mirometers diameter. Particles too small to be impacted on the last collection plate are collected in the backup filter. Optional accessories allow for additional research operations at 60 and 90 PLM.

Key Features:

  • Sample wet or dry particulates
  • Gravimetric analysis allows reference method precision
  • Ease of operation and calibration
  • Particle bounce and wall losses virtually eliminated
  • High mass collection and high flow rate
  • Gravimetric or chemical sample analysis
  • Stainless steel, glass, and filter substrates available
Additional Information:

  • Each sampler is comprised of eight aluminum stages that are held together by three spring clamps and gasketed with O-ring seals, and contain multiple precision-drilled orifices.
  • Ambient gases enter the inlet cone and cascade through the succeeding orifice stages with successively higher orifice velocities from Stage 0 to Stage 7.
  • Successively smaller particles are inertially impacted onto the collection plates and submicrometer particles, which are not collected by the last collection plate, are caught in the backup filter which is an integral part of the impactor immediately downstream from Stage 7.
  • Stage 0 is an orifice stage only, while Stage 8 is a collection stage only. Each sampler requires a flow rate of exactly 28.3L/min. (1 cfm) for maximum efficiency.

Compliance: The Andersen 20-800 series design is specifically cited within various world pharmacopeia (e.g., United States Pharmacopeia Chapter 601 "USP <601>") to characterize metered-dose (MDI) and dry powder-dose inhalers (DPI), nebulizers, nasal sprays, and other pulmonary drugs. Non-Viable Cascade Impactors are especially relevant during research, quality assurance and equivalency testing. Various introduction kits are available for these specialized applications (see USP Accessory Parts). The testing of inhalation drugs relates well to the cascade impactor. The size ranges collected are considered inhalable (generally <10um). Just as the inhalation drugs should consistently arrive within the respiratory system into their target regions, the various stages represent the cut-off sizes where deposition occurs within the lungs.

All new impactor systems undergo an ACIVIS inspection before shipping and are flow calibrated with a factory supplied vacuum pump where applicable. A unique serial number is given to multistage system to further track system history and allow data retrieval. The serial number is imprinted on each stage adjacent to the stage number.


Recommended for:
  • Pharmaceutical applications
  • Studying ventilation
  • Indoor or outdoor air quality
  • Hazardous waste sites
  • Emergency response situations

 
 
 
 
 
 
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