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ThermoScientific
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Amidites for DNA synthesis – TheraPure*

Thermo Scientific* TheraPure DNA Phosphoramidites are ideal for the most demanding applications of synthetic DNA oligonucleotides due to controlled levels of critical reactive impurities, controlled water content, and ultra high purity.
 
 
 
 
 
  • TheraPure phosphoramidites are designed for customers that require highly defined impurity profiles and strictly controlled manufacturing processes
  • Rigorously controlled manufacturing processes minimize levels of reactive P(III) impurities which could be incorporated into the oligonucleotide product and/or result in the accumulation of by-products which can be difficult to remove during purification
  • Limited residual water improves amidite stability, eliminating the interference with oligonucleotides synthesis that can be caused by excessive water
Process and Supply Chain Control:

  • A controlled raw material supply chain and established vendor partnerships ensure consistency and security of supply
  • All TheraPure products use synthetic nucleoside sources from materials of no known animal origin
  • Processes are strictly controlled and monitored from material procurement through final QC and product release under ISO9001 standards, providing batch-to-batch reproducibility
  • All TheraPure DNA phosphoramidites are supplied with lot-specific quality control data including HPLC and phosphorous NMR analyses
Flexible Packaging:

  • Common pack sizes fit most commercially available synthesizers and are in stock for immediate delivery
  • Custom and bulk packaging, including multikilogram lots, are available

 
 
 
 
 
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