July 1, 2012
Thermo Scientific Nunc Edge plate and Tecan Infinite 200 PRO multimode reader enable long-term cell-based experiments
ROCHESTER, NY (July 1, 2012) - Thermo Fisher ScientificTM Inc., the world leader in serving science, today announced that the TecanTM Infinite 200 PROTM multimode reader with Gas Control Modules (GCM) is optimized to work with Thermo ScientificTM NuncTM Edge plates to enable long-term cell-based studies over several days. Tecan has included Nunc EdgeTM plate specifications in all of its reader software, saving valuable equipment setup time.
The Nunc Edge plate incorporates large perimeter evaporation buffer zones that eliminate well-to-well variability while reducing the overall plate evaporation rate to less than two percent after seven days of incubation. Researchers found that by incorporating the GCM and the unique evaporation moat feature of the Nunc Edge Plate, they are able to control CO2 and O2 measurement inside the reader's chamber. This prevents an unwanted pH shift that could result in loss in cell viability, proliferation stop or cell death, and it enables use of all of the wells in the 96-well plate without "edge effect." Edge effect commonly occurs during prolonged incubations, with evaporation occurring in the outer 36 wells of a 96-well-plate format, negatively impacting cell viability.
The companies have produced an application note as part of a co-marketing agreement, Analyzing biological processes long-term cell-based kinetics using Tecan's GCM and the Thermo Scientific Nunc Edge Plates, which validates this capability. Additional posters, co-marketing and collaborative pieces will be developed to further enhance the relationship between Tecan’s reader capabilities and Thermo Scientific Nunc microplates.
About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of more than $10 billion, we have approximately 35,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through two premier brands, Thermo Scientific and Fisher Scientific, which offer a unique combination of continuous technology development and the most convenient purchasing options. Our products and services help accelerate the pace of scientific discovery, and solve analytical challenges ranging from complex research to routine testing to field applications. Visit www.thermofisher.com.