DXRxi imaging composite


Conferences/Demo       Webinars       Video

Graphene Applications        Pharma Applications        Geology Applications



DXRxi microscope with OMNICxi imaging software

The Thermo Scientific™ DXR™xi Raman imaging microscope enables users across many disciplines to quickly create information-rich chemical images without Raman expertise or a deep learning curve. It features a microscopy-first design that uses image-centric operation and built in spectroscopic profiling.


Introducing the DXRxi Raman imaging microscope

  • Save time with walk-up-and-run operation regardless of user skill level. Finally, high performance chemical imaging accessible to all
  • Optimize imaging parameters in real-time on-screen to visualize your data faster
  • Maximize sample throughput with intuitive workflow for demanding applications
  • Ensure accurate measurements
    • autoalignment and calibration – no tools required
    • automatic background compensation
  • Adaptable configuration by any user within seconds
    • change the pre-aligned laser, filter and gratings without any tools; expand your ability to take on most any sample
  • Accelerate progress across your organization with the expertise already built into the instrument
    • deep knowledge isn't required to set up the instrument, collect data or analyze results
    • share the instrument with multiple departments, getting more done with a single instrument
    • automatic feature recognition and powerful component identification simplify your analysis time

Reveal the unanticipated with the DXRxi Raman imaging microscope



Advancing research from materials science to pharmaceuticals


Upcoming webinars

January 31, 2015

Check back soon for details on an upcoming webinars covering geological analysis and carbon nanomaterial characterization, both using Raman imaging.

Visualizing, Characterizing, and Analyzing Pharmaceutical Constituents with Raman Imaging

January 31, 2015

45 minutes 
Presenter: Dr. Robert Heintz, Raman Applications Specialist, Thermo Fisher Scientific

Pharmaceutical formations are typically complex mixtures that need to be carefully verified and understood. Raman spectroscopy is a proven method for identifying and verifying the presence of a variety of different components and providing detailed information on molecular structure and chemical environments.  Raman imaging adds a spatial dimension to the analysis and extends the power of Raman spectroscopy across the sample. Some of the applications of Raman imaging relevant to pharmaceutical evaluations include:

  • Revealing  spatial distribution of components -  homogeneity and content uniformity
  • Assessing particle size including relative percentages of components
  • Differentiating and displaying  chemically similar components such as polymorphs
  • Quickly surveying larger areas and conducting detailed studies of smaller areas

watch on demand

Rethinking Raman Imaging: Advanced Materials Characterization

January 31, 2015

Hosted through Materials Today

Rapid and unambiguous results are vital for applying Raman imaging, a powerful technique, to the most difficult research challenges. 

  • Get an in-depth look at Raman imaging for geological materials and in characterizing monolayer graphene growth processes
  • Learn about recent advances in Raman imaging as an essential materials characterization tool
  • Participate in a live question and answer session to address your research needs
  • Receive essential technical information on getting the most out of Raman imaging in your lab

Watch On Demand

Rethinking Raman Imaging:Turning Data into Answers

January 31, 2015

Hosted through C&E News

We’ll show you how we’re rethinking Raman imaging to focus on turning your data into answers. With an image-centric approach to data interpretation, the new DXRxi Raman imaging microscope is designed to yield expert results for all users from basic to advanced.

See how the right Raman imaging system can uncover microscopic detail over large areas in record time. This broad overview will provide the essential technical information you need to make an informed decision about how to make Raman imaging work for you.

Watch On Demand


Stop by the Thermo Scientific booth at any of these remaining 2014 conferences to see the new DXRxi Raman imaging microscope!

  • American Vacuum Society
  • Fall Materials Research Society Meeting


If you can't join us at an upcoming conference use our literature download form to request a demo. Let us know if you'd like more information or to talk with a specialist about how the DXRxi microscope could be the ideal addition to your lab. See it in action today!


Graphene Raman chemical image composite

Carbon/Graphene Applications

January 31, 2015

Carbon nanomaterials have a niche in materials science due to their exceptional electronic, thermal, mechanical, optical and magnetic properties, creating potential applications in a wide range of fields. Raman spectroscopy is an integral part of carbon nanomaterial research because it plays a vital role in the characterization of these materials.

Application Note: Uncovering the Secrets Governing the Chemical Vapor Deposition of Graphene with Rapid Raman Imaging
One major challenge currently facing the graphene industry is the difficulty in controlling the quality of graphene sheets when produced over large areas using industrial scale techniques. The key to solving this challenge lies in gaining a thorough understanding of the synthetic methods used to fabricate macro-sized single-layer graphene films.

Application Note: Graphene Protective Coating Capabilities Investigated by Rapid Raman Chemical Imaging
Graphene has demonstrated exceptional barrier properties, being impenetrable to even helium. Coupled with the fact that the material is also optically transparent, this behavior has attracted intense interest in the material science area towards using graphene as a barrier layer in a variety of applications. This application note presents preliminary work investigating the protective capabilities of graphene employing the use of rapid Raman imaging.

Download the App Notes

Pharma Raman chemical images

Pharmaceutical Applications

January 31, 2015

Raman imaging is a useful tool where large areas of the sample can be analyzed and still preserve the spatial information. Covering larger areas of the sample provides confidence knowing that important areas are not being missed. The vast amounts of data generated by Raman imaging gives a more statistically relevant analysis of the sample.

Application Note: Visualizing Content Distribution in Tablets with Raman Imaging
There are many types of pharmaceutical formulations with  analytical problems such as identifying, verifying and evaluating the component distribution, chemical and molecular structure. This application note focuses on the rapid evaluation of whole tablets using Raman imaging to identify and evaluate the spatial distribution of the tablet components in a fast and efficient manner.

Application Note: The Analysis of Low Dose Tablets and Polymorphs Using Raman Imaging
Raman spectroscopy can distinguish between polymorphs, which are the same chemical compounds occurring in different crystalline forms. Polymorph identification is an important analysis step as these variations can affect how the drug is delivered and its therapeutic effectiveness. This application note focuses on using Raman imaging for evaluating the spatial distribution of active pharmaceutical ingredients in lower concentration tablets including the differentiation of polymorphs.

Application Note: Evaluating Active Ingredients in Pharmaceutical Hot Melt Extrusion Products with Raman Imaging
Hot melt extrusion production is an attractive alternative to traditional methods for pharmaceutical products. Raman spectroscopy can identify and verify the presence of different components and contaminants in various formulations.

Download the app notes


Geology Raman chemical image composite

Geological Applications

January 31, 2015

Raman spectroscopy is an established analytical technique for geological samples. It not only provides a fast and efficient way of identifying specific materials, but it also provides considerable information for:

  • molecular structure and chemical environments
  • identifying various minerals using ever expanding databases
  • evaluating phases of the same or very similar chemical composition
  • characterizing inclusions within samples without the need to expose the inclusions
    • encompasses different solid, liquid or gaseous phases within the inclusion
  • analyzing archived samples that have been mounted under glass cover slips
  • residual pressure and stress within a sample by looking at shifts in the Raman peaks

Application Note: An Exceptional View of Geological Materials with Raman Imaging covers these topics and more. Download and read the note today!

download the app note

OMNICxi Software for the DXRxi

OMNICxi Imaging Software

January 31, 2015

Thermo ScientificTM OMNICTMxi software will not only seem intuitive, but it will also look familiar. Inspired by optical, scanning electron and atomic force microscopes, this image-centric software naturally complements what you already know. The chemical and morphological analysis is built into the microscope platform rather than requiring you to learn a new spectroscopic technique or theory.

Spend less time looking and more time understanding. Quickly identify regions of interest and automatically find and target particles, defects, contaminants and other unique features for detailed analysis.

Don't wait until the end of your collection for results. Perform spectral database searches with display results in real time during data collection.

Never forget to collect a background again! Background collection is automatically done for you.

No more long collections only to find settings were not ideal. Utilize the real-time parameter tuning with immediate visual display.

Always be ready. Real-time visual status of the system readiness maximizes your instrument use time.