Ultimate core performance to maximize your investment

Accucore UHPLC and HPLC Columns

Thermo Scientific™ Accucore™ HPLC, nanoLC and UHPLC columns are a family of products based on Core Enhanced Technology™ that provide ultimate core performance and allow you to maximize your investment.

  • Solid core particles for fast separations with superb resolution
  • Wide range of phases to meet all your separation needs
  • Exceptionally rugged and easy to use columns

Accucore core technology

Explanation of Core Enhanced Technology

Accucore Vanquish UHPLC Columns deliver core performance

The next-generation UHPLC column features 1.5μm solid core particles and combines the benefits of a solid core material and the increased chromatographic efficiency of a sub-2μm particle. 

Modern analytical laboratories continue to be driven towards higher throughput workflows which require better, more and easier separations at a reduced cost. Thermo Scientific™ Accucore™ Vanquish UHPLC columns enable you to achieve this by delivering:

  • Better separations: High efficiency enables the resolution of very complex mixtures 
  • More results: High efficiency is maintained at high flow rates enabling fast separations 
  • Easier interactions: Seamless workflow solution (column, system and data processing combined), allows for simple and easy-to-implement separations

Ordering information

Description Particle Size Length Diameter (ID) Part Number
Accucore Vanquish C18+ 1.5μm 100mm 2.1mm 27101-102130

The Vanquish UHPLC System Offers Better Separations, More Separations, Easier Separations 

The Vanquish UHPLC system and Accucore Vanquish UHPLC columns have been designed around the user to solve chromatographic challenges by: 

  • Separating more complex samples in less time with 1500 bar pressure and low dispersion volumes 
  • Maintaining peak shapes due to consistent temperature distribution
  • Keeping up with faster separations with increased sample capacity 
  • Seeing more of the sample with lower limits of detection and improved quantification 
  • Getting that extra level of identification, by partnering with state-of-the-art mass spectrometers 
  • The total solution offers operational simplicity with efficient control and Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System
Vanquish UHPLC System
Chromeleon 7.2 Simply Intelligent



Introducing the Accucore HPLC Columns

Using core-enhanced technology, Thermo Scientific™ Accucore™ HPLC Columns offer high speed, superb resolution separations compared to traditional larger fully porous particles and generate lower backpressures than UHPLC sub-2µm particles.

Ultimate Chromatographic Performance at Low Backpressures

Dafydd Milton introduces new Accucore HPLC column technology that enables high-speed, high-resolution separations, with backpressures lower than those associated with UHPLC.